About us
We are 15 young scientists from 13 different countries researching different imaging modalities and their optimisation for monitoring Mg-based implants in this training network. Everyone has different objectives to optimise the imaging for this new class of biodegradable Mg-based implants, thereby pushing the safety of degradable magnesium implants even further.
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MgSafe final meeting Pisa, Italy, April 2022
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Early Stage Researchers visiting Hereon labs at Geesthacht, Germany, November 2021
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Graz, Austria, December 2019
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Brüttisellen, Switzerland, September 2019
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Oslo, Norway, June 2019

Begüm defended her doctoral thesis "In vivo characterization of designated magnesium materials by microCT and fluorescence imaging in rats" at the Medical University in Graz.
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Begüm at the first MgSafe meeting in Oslo
Begüm Okutan from the Medical University of Graz works on the in-vivo characterization of magnesium-based implants and the working title of her PhD is: In vivo characterisation of designated Mg materials (pins and wires) by µCT and fluorescence imaging.

Romy successfully defended her doctoral thesis "Large Animal in vivo Characterization of Designated Full Size Magnesium Implants by clinical CT and µCT in a Juvenile Sheep Model" at the Medical University in Graz.
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Romy at the first MgSafe meeting in Oslo
Romy Marek from the Medical University of Graz works within the MgSafe project on: Large animal in vivo characterisation of designated full size Mg implants (K-Wires, screws) by clinical CT.
Maryam Rahmati is the first MgSafe ESR to defend her doctoral thesis

Maryam Rahmati successfully defended her doctoral dissertation ‘In vivo evaluation of biomaterials for bone regeneration applications using advanced imaging techniques’:
PhD defence Maryam
Maryam at the first MgSafe meeting in Oslo
During her PhD studies in MgSafe, Maryam Rahmati from the University of Oslo (UiO) works on the histological validation of advanced bone-implant imaging techniques. She is focusing on the assessment of implant degradation and incorporation by histological and immuno‐histochemical analyses and the comparison of histological evidence with advanced imaging techniques.
Heithem successfully defended his thesis

2023-11-17 Heithem successfully defended his thesis "Biodegradable magnesium implants, immunomodulation, and tissue repair/regeneration" at the University of Gothenburg
Heithem interview on his PhD project (UGOT)
PhD thesis 'Biodegradable magnesium implants, immunomodulation, and tissue repair/regeneration'

Cover illustration of Heithem Ben Amara's thesis. Tissue response to biodegradable magnesium implants (Mg). Histology of bone (1) and soft tissue (2,3) at the interface with Mg. Gas bubbles from Mg in tissues studied by electron microscopy (4), immunohistochemistry (5), and image analysis (6)

© Peter Thomson, IngaBritt och Arne Lundbergs Forskningsstiftelse
Heithem at the first MgSafe meeting in Oslo
Heithem Ben Amara broke his arm when he was a child and still remembers the operation, when the fixing screw was removed. Today he is a PhD student at University of Gothenburg (UGOT) and researches biodegradable magnesium based implants. Within MgSafe, he will focus on molecular and structural analyses during bone healing and soft-tissue inflammation.
Christina at the first MgSafe meeting in Oslo
Christina Yiannakou from Cyprus is doing her PhD within the EU-project MgSafe at Hannover Medical School (MHH). The working title of her PhD is: MRI development for Mg implants to study inflammation.
Leon at the first MgSafe meeting in Oslo
Leon Riehakainen from Estonia is working at Consiglio Nazionale delle Ricerche Istituto di Fisiologia Clinica in Pisa (CNR-IFC) and doing his PhD on multimodal imaging of bone regeneration and remodelling after implantation of degradable Mg-based devices in experimental animal models with a special focus on PET imaging.
Valeria defended her thesis summa cum laude!

22 April 2024: Eduarda defending her thesis entitled 'Biochemical and biohumoral studies of bone regeneration and remodelling after implantation of magnesium pin.'
We are incredibly proud to share that Eduarda Silva has brilliantly defended her PhD thesis with a Summa Cum Laude distinction! A tremendous accomplishment that speaks volumes about her dedication and the quality of her work.
This significant milestone was coordinated with the help of Dr. Luca Menichetti and our colleagues at the Consiglio Nazionale delle Ricerche. The defense took place at the prestigious Scuola Superiore Sant'Anna, showcasing Eduarda's innovative research on magnesium degradable implants, which are pivotal for orthopaedic applications. Her work emphasizes optimizing the biocompatibility and degradation rate of Mg-Alloy implants and offers valuable insights into systemic responses and biomarker assessments for tissue regeneration and implant osseointegration.

A revolutionary aspect of Eduarda's work lies in her examination of systemic biomarker effects on implanted Mg alloy implants and correlating these to imaging techniques. This approach enables crucial insights into how Mg alloy implants perform in humans, which is vital as clinical follow-up with these and other implants poses significant challenges. The limitations on the frequency of X-rays and CBCT scans restrict close monitoring of implant performance. Traditional clinical signs like pain, redness, or swelling are inadequate indicators of implant functionality. Thus, Eduarda's research provides a groundbreaking method to enhance our understanding and monitoring of implant integration and performance in clinical settings.
Eduarda's research contributes significantly to our understanding and paves the way for enhancing the clinical application of these promising materials. We are excited about the potential impacts of her findings on the field of biomaterials and patient care.
Heartfelt congratulations to Eduarda on her well-deserved success—we look forward to the great things she will continue to achieve in her career.
Eduarda at the first MgSafe meeting in Oslo
Eduarda's task within MgSafe are biochemical and biohumoral studies of bone regeneration and remodelling after implantation. She is affiliated with Consiglio Nazionale delle Ricerche Istituto di Fisiologia Clinica in Pisa (CNR-IFC).
Wajaht sucessfully defended his thesis


Dr. Wajahat Hassan (left) and his supervisor Dr. Peyman Mirtaheri
29 August 2023 Wajahat sucessfully defended his thesis 'In vivo monitoring of tissue oxygenation in response to a Mg-based biodegradable implant using NIR spectroscopy' at Oslo Metropolitan University, Norway.
Congratulations with this great success!
Wajahat at the first MgSafe meeting in Oslo
Hafiz Wajahat Hassan is working on spectral analysis at Oslo Metropolitan University (OsloMet). His focus is on the In vivo monitoring of the body reaction to the implant by using a novel optical probe and near IR spectroscopy.

She started in October 2019 at Warsaw University of Technology (WUT) in the Materials Design Division. Her task in the network is the characterisation of corrosion layer structure and composition in explants.
Hanna at the first MgSafe meeting in Oslo
Hanna started her PhD within MgSafe at the Helmholtz-Zentrum Hereon (Hereon) April 2019. She works at the Hereon-outstation at DESY and focusses on the structural characterisation of explants by synchrotron radiation. One objective is the imaging of magnesium implants in native tissue environment.
Kamila at the first MgSafe meeting in Oslo
Kamila Iskhahova started her PhD at the Helmholtz-Zentrum Hereon (Hereon). Her aim is to link ultrastructure and biomechanical properties of bone adjacent to biodegradable magnesium implants. She studies the biomechanical properties of the bone-implant surface and the adjust bone tissue by synchrotron radiation at the Hereon outstation at DESY.

Marwa at the first MgSafe meeting in Oslo
Marwa Chaabane from Scanco Medical AG is a computer scientist. During her PhD she will work on the development of a system to join 2D, 3D and 4D data and to describe their relative relation in space & time. The working title of her thesis is Software development for management and visualisation of multimodal data.

Mostafa started his PhD at MRI.Tools in Berlin (MRI.T). He works on his thesis titled En route to the clinic: MR safety - MR antenna design tailored for magnesium alloy implants.
Jonathan at the first MgSafe meeting in Oslo
PhD student Jonathan Espiritu from Canada works at Syntellix in Hannover (SYN) and researches within the EU project MgSafe on MR safety and the influence of Mg implants on MR signals.
Valeria defended her thesis summa cum laude


from left to right: Dr. Jithin Jose, Prof. Regine Willumeit-Römer, and Dr. ing. Valeria Grasso
28 April 2023 Valeria very sucessfully defended her thesis 'High-resolution ultrasound and photoacoustic imaging for human applications' at the Kiel University, Germany.
Congratulations with this great success!
Valeria at the first MgSafe meeting in Oslo
Valeria Grasso is a PhD student working at FujiFilm SonoSite (VSI) in Amsterdam. She focusses on high-resolution ultrasound and photoacoustic imaging for human applications.